Comprehensive Celiac Profile Test – Gluten Sensitivity & Celiac Disease Screening

Description

Celiac Profile Disease Antibody Panel – Comprehensive Gluten Sensitivity Test

The Celiac Profile Disease Antibody Panel from Lab Tests Dubai is a comprehensive blood test that detects immune system antibodies produced in response to gluten providing a highly accurate diagnosis of celiac disease and gluten sensitivity.

Unlike basic tests, this 4-parameter panel includes:

• ✅ Tissue Transglutaminase Antibodies (tTG IgA & IgG) – the gold standard for celiac screening
• ✅ Endomysial Antibodies (EMA IgA & IgG) – highly specific for celiac disease
• ✅ Deamidated Gliadin Peptide Antibodies (DGP IgA & IgG) – useful in children and IgA-deficient patients
• ✅ Total Immunoglobulin A (IgA) – rules out IgA deficiency, which can cause false-negative results

This test is essential for:

• Diagnosing celiac disease in symptomatic individuals
• Evaluating non-responsive IBS, anemia, or osteoporosis
• Screening family members of celiac patients (1 in 10 are affected)
• Investigating chronic fatigue, brain fog, or dermatitis herpetiformis
• Confirming diagnosis before intestinal biopsy

With results in just 7 days, Lab Tests Dubai helps gastroenterologists and patients detect celiac disease early so you can heal your gut, restore nutrients, and stop the damage.

Available with home blood collection, this panel ensures accurate, private, and stress-free testing so you can get answers without delay.

Why You Need This Test

If you’ve had chronic bloating, diarrhea, anemia, or fatigue and no one has found the cause this test could reveal celiac disease, an autoimmune reaction to gluten that damages your small intestine and prevents nutrient absorption.

You need the Celiac Profile if:

• You have chronic digestive issues (diarrhea, constipation, gas)
• You suffer from unexplained iron-deficiency anemia
• You have fatigue, brain fog, or joint pain
• You’ve been diagnosed with Type 1 diabetes, Hashimoto’s, or autoimmune thyroid disease
• You have osteoporosis or recurrent fractures
• You have a family history of celiac disease
• You’re planning a gluten-free diet but want confirmation first

This test helps:

• Confirm or rule out celiac disease
• Avoid unnecessary biopsies with accurate antibody results
• Diagnose silent or atypical celiac (no gut symptoms)
• Guide a lifelong gluten-free diet
• Prevent long-term complications

Early testing  gut healing and restored energy.

Symptoms That Indicate This Test

Consider the Celiac Profile if you experience:

✅ For Classic Celiac (Digestive):

• Chronic diarrhea or constipation
• Bloating, gas, or abdominal pain
• Unexplained weight loss
• Pale, foul-smelling stools (steatorrhea)

✅ For Atypical or Silent Celiac:

• Iron-deficiency anemia (not corrected by supplements)
• Osteoporosis or low bone density
• Fatigue, depression, or brain fog
• Skin rash (dermatitis herpetiformis – itchy, blistering)
• Infertility or recurrent miscarriages
• Neurological issues (migraines, neuropathy)

✅ For High-Risk Individuals:

• First-degree relative with celiac
• Type 1 diabetes, autoimmune thyroid, or Down syndrome

These signs may point to gluten-induced autoimmunity and this test helps start the right treatment.

Natural Production: How Gluten Triggers Autoimmunity

In celiac disease, gluten (a protein in wheat, barley, rye) triggers an abnormal immune response:

• Gluten is partially digested into gliadin
• Gliadin crosses the gut lining (especially if leaky)
• The immune system attacks it using tTG (tissue transglutaminase)
• Antibodies form: anti-tTG, anti-EMA, anti-DGP
• The immune system mistakenly attacks the intestinal villi → villous atrophy

This leads to:

• Malabsorption of iron, calcium, B12, folate
• Chronic inflammation
• Increased risk of other autoimmune diseases

The Celiac Profile detects these autoantibodies a clear sign of immune attack on the gut.

What Happens If Untreated? Risks of Ignoring Celiac Disease

Ignoring celiac disease can lead to:

⚠️ Permanent Gut Damage – even with mild symptoms
⚠️ Severe Nutrient Deficiencies – anemia, osteoporosis, neuropathy
⚠️ Infertility & Pregnancy Complications
⚠️ Increased Cancer Risk – intestinal lymphoma (rare but serious)
⚠️ Autoimmune Disorders – higher risk of thyroid disease, type 1 diabetes
⚠️ Neurological Damage – gluten ataxia, migraines

The good news? Celiac disease is 100% treatable with:

• Strict, lifelong gluten-free diet
• Nutritional supplementation
• Regular monitoring

Early testing  prevention of irreversible damage.

How to Prepare for the Test

To ensure accurate results:

✅ Continue eating gluten – at least 2 slices of bread per day for 6–8 weeks before the test
❌ Do NOT start a gluten-free diet before testing – it can cause false-negative results
✅ No fasting required
✅ Inform your doctor of:

• Current medications (steroids may suppress antibodies)
• Recent infections or GI illnesses

A single blood draw measures all 4 markers available at our labs or via home collection.

Test Overview: 4-Parameter Antibody Panel

Report Includes:

• Negative/Positive for each antibody
• IgA Status (to rule out deficiency)
• Clinical Interpretation (Likely, Possible, or Unlikely celiac)
• Recommendations for biopsy or diet changes

Note: A positive result should be followed by endoscopy with biopsy for definitive diagnosis.

Benefits of the Celiac Profile Antibody Panel

🔹 Highly Accurate & Comprehensive
Detects celiac even in IgA-deficient patients.

🔹 Identifies Silent Celiac
No gut symptoms? You can still have it.

🔹 Guides Gluten-Free Diet
Start with confidence, not guesswork.

🔹 Prevents Long-Term Damage
Stop malabsorption before it causes harm.

🔹 Peace of Mind
Know if gluten is your enemy.

If you’re suffering from bloating, fatigue, anemia, or unexplained symptoms, the Celiac Profile Antibody Panel gives you the answers you need in 7 days.