Germline HRR Panel with BRCA1 & BRCA 2
Germline HRR Panel with BRCA1 & BRCA 2 at Lab Tests Dubai costs AED 5,500 (VAT included), uses a whole blood (EDTA) sample and results are usually ready in 4–6 weeks. Book home collection across Dubai (AED 150) or visit our lab in Al Karama or Al Barsha 1 — no doctor referral needed.
Key facts
- Price (incl. VAT)
- AED 5,500
- Sample
- Whole blood (EDTA)
- Method
- Next-generation sequencing (NGS)
- Results in
- 4–6 weeks
- Home collection
- AED 150 per visit
- Doctor referral
- Not needed
What it measures
- ATM, BARD1, BRCA1, BRCA2, BRIP1, CDK12, CHEK1, CHEK2, FANCD2, FANCL, KRAS, MRE11, NBN, PALB2, PIK3CA, POLD1, POLE, PPP2R2A, PTEN, RAD50, RAD51, RAD51B, RAD51C, RAD51D, RAD52, RAD54L, TP53, XRCC2
The germline HRR panel uses next-generation sequencing to look for inherited changes in 28 genes, including BRCA1 and BRCA2, that are involved in homologous recombination repair (HRR), one of the ways cells fix damaged DNA.
What the test looks for
When DNA repair genes do not work properly, damaged DNA builds up and the risk of some cancers rises. Inherited changes in HRR genes such as BRCA1, BRCA2, PALB2, ATM and CHEK2 are linked to a higher risk of breast, ovarian, prostate and pancreatic cancer. Knowing about these changes can also help oncologists choose certain targeted treatments for people who already have one of these cancers.
“Germline” means the test uses your blood to look at the genes you were born with. The full list of 28 genes is shown on this page.
Who might consider it
- People with breast, ovarian, prostate or pancreatic cancer, when their oncologist wants to know about inherited HRR gene changes
- People with a strong family history of these cancers, after discussion with a doctor or genetic counsellor
If you only need BRCA1 and BRCA2 tested, the BRCA1 and BRCA2 germline test may be enough. For changes in the tumour itself, there is a somatic HRR panel.
Before you book
The test uses one blood sample. Our team can collect it at your home or office anywhere in Dubai, or you can visit our lab in Al Karama or Al Barsha 1. The lab asks for a signed consent form and your clinical and family history with the sample. Results are usually ready in 4–6 weeks. We recommend genetic counselling before and after testing.
Understanding your results
The report lists any harmful (pathogenic) variants, variants of uncertain significance, or no variants found. A harmful variant can affect your cancer risk and treatment options, and may be relevant to your relatives. Your oncologist or a genetic counsellor will explain the result and next steps.
Frequently asked questions
How much does the germline HRR panel cost in Dubai?
AED 5,500, VAT included. Home collection costs AED 150 per visit; there is no extra fee when you visit our lab in Al Karama or Al Barsha 1.
What does HRR mean?
Homologous recombination repair, a way cells repair damaged DNA. BRCA1, BRCA2, PALB2 and other HRR genes are part of it.
How is this different from a BRCA test?
A BRCA test looks at BRCA1 and BRCA2 only. This panel looks at 28 DNA repair genes, including BRCA1 and BRCA2.
What sample is needed and how long do results take?
One blood sample. Results are usually ready in 4–6 weeks.
Do I need a doctor’s referral?
No, you can book it directly, but we strongly recommend genetic counselling before and after testing.
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Book this test
No doctor referral needed. Home sample collection anywhere in Dubai for AED 150 per visit, or visit our lab in Al Karama or Al Barsha 1. Every price includes VAT.