Liquid HALLMARK (Liquid Biopsy)

Description

Liquid HALLMARK (Liquid Biopsy) – Comprehensive Cancer Detection and Monitoring

The Liquid HALLMARK Liquid Biopsy from Lab Tests Dubai is a revolutionary, non-invasive cancer testthat analyzes circulating tumor DNA (ctDNA) in your blood—offering a painless alternative to tissue biopsies for early detection, treatment monitoring, and recurrence surveillance.

Using ultra-deep next-generation sequencing (NGS) and Lucence’s proprietary AmpliMARK™ technology, this advanced blood test detects genetic mutations and biomarkers from over 50+ cancer types, including:

• Lung, breast, colorectal, liver, and ovarian cancers
• Cancers of unknown primary (CUP)
• Hereditary cancer risk markers

This test is essential for:

• Early cancer detection in high-risk individuals
• Monitoring treatment response (chemotherapy, targeted therapy, immunotherapy)
• Detecting minimal residual disease (MRD) after surgery
• Identifying recurrence before imaging shows changes
• Guiding personalized therapy based on tumor genetics

With results in just 8–10 days, Liquid HALLMARK empowers oncologists and patients to make data-driven decisions—so you can stay ahead of cancer with precision and peace of mind.

Available with home blood collection, Lab Tests Dubai ensures accurate, private, and stress-free testing—so you can monitor your health without hospital visits.

Why You Need This Test

If you’re at high risk for cancer, undergoing treatment, or in remission, this test could detect cancer earlier than scansand track your response in real time.

You need the Liquid HALLMARK Liquid Biopsy if:

• You have a strong family history of cancer (e.g., BRCA, Lynch syndrome)
• You’re a cancer survivor and want to monitor for recurrence
• You’re undergoing targeted therapy or immunotherapy
• You’re unable to undergo tissue biopsy (due to location or health)
• You have unexplained symptoms like weight loss or fatigue
• You want proactive cancer screening beyond routine exams

This test helps:

• Detect cancer earlier—before symptoms or imaging
• Monitor treatment effectiveness weekly or monthly
• Identify resistance mutations (e.g., EGFR, KRAS, PIK3CA)
• Avoid invasive biopsies
• Personalize your cancer care

Early insight = better outcomes and more control.

Symptoms That Indicate This Test

Consider the Liquid Biopsy if you experience:

✅ For Early Detection:

• Unexplained weight loss
• Persistent fatigue or weakness
• Chronic pain or discomfort
• New lumps or swelling
• Changes in bowel or bladder habits
• Persistent cough or shortness of breath

✅ For Monitoring:

• During chemotherapy or targeted therapy
• After surgery or radiation (for MRD)
• In remission with fear of recurrence

✅ For High-Risk Individuals:

• BRCA1/2, Lynch, or other hereditary syndromes
• Long-term smokers or asbestos exposure
• Chronic inflammatory conditions (e.g., IBD, cirrhosis)

These signs may point to hidden or recurring cancer—and this test helps start the right action.

Natural Production: How ctDNA Reveals Cancer

When cancer cells die, they release fragments of tumor DNA (ctDNA) into the bloodstream.

This circulating tumor DNA carries the same genetic mutations as the original tumor—making it a “liquid fingerprint” of cancer.

Key Facts:

• ctDNA levels correlate with tumor burden
• It can be detected months before imaging shows recurrence
• It reflects tumor heterogeneity (multiple mutations)
• It helps identify resistance mutations during treatment

The Liquid HALLMARK test uses AmpliMARK™ technology to:

• Enrich ctDNA from normal DNA
• Sequence over 100+ cancer-related genes
• Detect mutations at ultra-low frequencies (as low as 0.01%)

This is precision oncology in a blood test.

What Happens If Untreated? Risks of Ignoring Cancer Signals

Ignoring cancer signs or delaying monitoring can lead to:

⚠️ Late-Stage Diagnosis – Stage III/IV cancers with limited treatment options
⚠️ Metastasis – spread to liver, lungs, brain, bones
⚠️ Treatment Resistance – due to undetected mutations
⚠️ Reduced Survival Rates – drops significantly in advanced stages
⚠️ More Aggressive Therapy – chemotherapy, extensive surgery

The good news? Early detection and monitoring improve survival with:

• Less invasive treatments
• Targeted therapies based on genetics
• Faster intervention at recurrence

Early testing = more time, better quality of life.

How to Prepare for the Test

To ensure accurate results:

✅ No fasting required
✅ Continue your regular medications (inform your doctor of targeted therapies)
✅ Stay well-hydrated before blood draw
✅ Inform your doctor of:

• Recent treatments (chemo, radiation)
• History of cancer or family risk
• Current symptoms

A serum blood sample is collected via standard draw—available at our labs or via home collection.

Test Overview: Ultra-Deep Sequencing with AmpliMARK™

Report Includes:

• Detected Mutations (e.g., EGFR, KRAS, PIK3CA, BRAF)
• Variant Allele Frequency (VAF)
• Therapeutic Implications (FDA-approved drugs, clinical trials)
• Resistance Markers
• Recommendations for Oncologist

Note: Often used alongside imaging and tissue biopsy for full picture.

Benefits of the Liquid HALLMARK Liquid Biopsy

🔹 Non-Invasive & Painless
No surgery, no radiation—just a blood draw.

🔹 Early Detection Power
Find cancer before it spreads.

🔹 Real-Time Monitoring
Track treatment response monthly.

🔹 Guides Targeted Therapy
Match drugs to your tumor’s DNA.

🔹 Peace of Mind
Know your cancer status between scans.

If you’re fighting cancer, in remission, or at high risk, the Liquid HALLMARK Liquid Biopsy gives you the answers you need in 8–10 days.