Karyotyping - Products Of Conception (L)

The Karyotyping – Products of Conception (L) is a specialized cytogenetic test that analyzes fetal tissue collected after a miscarriage, stillbirth, or termination to identify chromosomal abnormalities such as aneuploidy, translocations, deletions, or duplications, common genetic causes of early pregnancy loss.

Up to 60% of first-trimester miscarriages are due to chromosomal errors. This test helps determine whether your loss was caused by a random genetic event or an underlying parental chromosomal issue, providing vital insights for future family planning.

Performed at Lab Tests Dubai using advanced cell culture and G-banding techniques, this test delivers accurate, lab-confirmed results that empower you and your healthcare provider to make informed decisions about next steps, whether it’s trying again naturally, pursuing IVF with PGT, or seeking genetic counseling.

We offer this service with the highest level of clinical precision and compassionate care, recognizing the emotional weight behind every sample.

Why You Need This Test

You need the Karyotyping – POC Test if:

• You’ve experienced a first or recurrent miscarriage
• You’re seeking answers beyond “it just happened”
• You want to know if the loss was due to a chromosomal defect
• You’re planning future pregnancies and want to assess risk
• Your doctor suspects a genetic cause based on ultrasound or history

This test transforms grief into knowledge, helping you move forward with clarity, hope, and a personalized plan.

This test is strongly recommended when:

• Pregnancy ends unexpectedly in the first or second trimester
• Ultrasound showed fetal growth restriction or structural anomalies
• You’ve had two or more consecutive miscarriages (recurrent pregnancy loss)
• A D&C or MTP procedure yielded fetal tissue
• You’re undergoing fertility evaluation after loss

Even one unexplained loss warrants investigation, because understanding the “why” can change your journey.

Natural Production (Clarification: Chromosomes & Errors)

Chromosomes are naturally inherited — 23 from the egg, 23 from the sperm — forming a healthy embryo with 46 total. However, errors during fertilization or early cell division can lead to:

• Aneuploidy: Extra or missing chromosomes (e.g., Trisomy 16, Monosomy X)
• Structural changes: Translocations, deletions, inversions
• These often result in non-viable pregnancies

This test identifies those abnormalities in the products of conception, distinguishing between isolated events and potential hereditary factors.

How to Prepare for the Test

Important: This test requires fetal tissue, not blood or saliva.

• Sample Requirements:

• Fresh or FFPE tissue: Products of conception collected during D&C, MTP, or delivery

• Must include viable chorionic villi or fetal parts

• Submit within 24 hours of collection (fresh), or use paraffin block/slides

• Shipping Instructions:

• Fresh tissue: Ship refrigerated (2–8°C) in sterile saline or transport medium

• FFPE block/slides: Room temperature, dry packaging

• Mandatory:

• Completed Genetic Test Request Form (TRF)

• Clinical details including gestational age, ultrasound findings, number of prior losses

• Patient consent form

Our team supports secure logistics and coordination with clinics/hospitals across the UAE.

Test Overview