DNA methylation pathway extended profile
DNA methylation pathway extended profile at Lab Tests Dubai costs AED 5,900 (VAT included), uses a whole blood (EDTA) or saliva sample and results are usually ready in 25–30 days. Book home collection across Dubai (AED 150) or visit our lab in Al Karama or Al Barsha 1 — no doctor referral needed.
Key facts
- Price (incl. VAT)
- AED 5,900
- Sample
- Whole blood (EDTA) or saliva
- Preparation
- For a saliva sample: no food, drink or smoking for at least 30 minutes before. No preparation is needed for a blood sample.
- Method
- Microarray genotyping
- Results in
- 25–30 days
- Home collection
- AED 150 per visit
- Doctor referral
- Not needed
The DNA methylation pathway extended profile looks at variations in 16 genes involved in methylation, folate and vitamin B12 metabolism and related processes. It is a wellness and nutrition genetics test, not a diagnostic test for a disease.
What the test looks for
Methylation is a chemical process the body uses constantly, for example to recycle homocysteine, make neurotransmitters and switch genes on and off. It depends on nutrients such as folate, vitamin B12, vitamin B6 and choline, and on enzymes made from genes such as MTHFR, MTR and MTRR.
This profile uses a microarray to genotype common variations in these genes: ACE, AHCY, BHMT, CBS, COMT, DHFR, FOLR, FUT2, MAT1, MTHFD1, MTHFR, MTR, MTRR, SHMT, SHMT2 and VDR. Some of these variations are known to change how efficiently an enzyme works; for others, the evidence is still developing.
Who might consider it
- Adults interested in how their genes relate to folate, B vitamins and homocysteine
- People whose doctor or dietitian wants more detail than a single MTHFR test
- People with a raised homocysteine level who want to explore genetic factors with their doctor
Before you book
You can give a blood sample or a saliva sample. For saliva, do not eat, drink or smoke for at least 30 minutes before. Our team can collect the sample at your home or office anywhere in Dubai, or you can visit our lab in Al Karama or Al Barsha 1. The lab asks for a signed consent form and your relevant medical history with the sample, as it does for all genetic tests. Results are usually ready in 25–30 days.
Understanding your results
The report lists your genotype for each gene. These results describe common variations; they do not diagnose a condition, and having a variant does not mean you will have a health problem. Blood tests such as homocysteine, folate and vitamin B12 show how your body is actually working. Please discuss any changes to supplements, diet or medicines with your doctor rather than acting on genotypes alone.
Frequently asked questions
How much does the DNA methylation pathway extended profile cost in Dubai?
AED 5,900, VAT included. Home collection costs AED 150 per visit; there is no extra fee when you visit our lab in Al Karama or Al Barsha 1.
Which genes are included?
ACE, AHCY, BHMT, CBS, COMT, DHFR, FOLR, FUT2, MAT1, MTHFD1, MTHFR, MTR, MTRR, SHMT, SHMT2 and VDR.
Can I give saliva instead of blood?
Yes. Avoid food, drink and smoking for at least 30 minutes before giving a saliva sample.
How long do results take?
Results are usually ready in 25–30 days.
Should I change my supplements based on the result?
Please discuss it with your doctor first. Genotypes describe common variations and are best read alongside blood tests such as homocysteine, folate and vitamin B12.
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Book this test
No doctor referral needed. Home sample collection anywhere in Dubai for AED 150 per visit, or visit our lab in Al Karama or Al Barsha 1. Every price includes VAT.