Cyfra 21-1 – Tumor Marker Analysis
550,00 د.إ
The Cyfra 21-1 test is a specialized tumor marker analysis. It measures the levels of Cytokeratin 19 fragments in your blood serum.
Sample Type : Serum
Methodology : TBA
TAT : 10 Days
Description
Cyfra 21-1 Lab Test: Comprehensive Tumor Marker Analysis for Lung and Bladder Cancer
In the world of oncology, information is power. When fighting complex conditions like Non-Small Cell Lung Cancer (NSCLC) or bladder cancer, “watch and wait” is not a strategy; proactive surveillance is.
This is where the Cyfra 21-1 lab test comes in. It is more than just a blood test; it is a molecular radar. By detecting specific protein fragments released by cancer cells, this test provides oncologists with critical insights into how a disease is behaving.
Whether you are at high risk due to a history of smoking, or you are currently navigating a treatment plan, the Cyfra 21-1 test offers data that can guide life-saving decisions.
What is the Cyfra 21-1 Lab Test?
The Cyfra 21-1 test is a specialized tumor marker analysis. It measures the levels of Cytokeratin 19 fragments in your blood serum.
The Science Made Simple:
- Cytokeratin 19 is a structural protein found in epithelial cells, which line our organs and hollow structures.
- When these cells are healthy, these proteins stay put. However, when cells die or break down, often aggressively in cancer, they release fragments into the bloodstream.
- The Cyfra 21-1 test captures these fragments. Elevated levels suggest rapid cell turnover, a hallmark of certain malignancies.
While various tumor markers exist, Cyfra 21-1 is particularly sensitive to Non-Small Cell Lung Cancer (NSCLC) and Bladder Cancer (Transitional Cell Carcinoma).
Why This Test is Essential for Your Care Journey
Cancer is dynamic. It changes in response to chemotherapy, radiation, and surgery. A static scan cannot always show these microscopic changes immediately. The Cyfra 21-1 test serves three vital functions:
- Diagnostic Aid: If a patient presents with symptoms like a persistent cough or blood in the urine, an elevated Cyfra 21-1 level can point doctors toward a diagnosis of NSCLC or bladder cancer, especially alongside imaging tests.
- Treatment Monitoring: This is the test’s strongest application. As you undergo chemotherapy, your doctor tracks your levels. Dropping levels usually mean the treatment is working. Rising levels may signal resistance.
- Surveillance & Recurrence: Even after successful treatment, “silent” cancer cells can return. Regular Cyfra 21-1 testing can catch a recurrence months before a tumor is visible on a CT scan.
Red Flags: When Should You Consider This Test?
Tumor markers are rarely used for screening the general population but are crucial for those at risk or with symptoms. You should discuss this test with your provider if you have:
- Respiratory Symptoms: A persistent cough, changes in voice, coughing up blood (hemoptysis), or recurrent chest infections.
- Urinary Symptoms: Blood in the urine (hematuria) or painful urination, which are classic signs of bladder issues.
- Risk Factors: A significant history of smoking, exposure to asbestos or industrial chemicals, or a family history of lung or bladder cancer.
- Unexplained Weight Loss/Fatigue: Severe fatigue that impacts daily life, combined with weight loss without trying.
The Risks of Ignoring Biomarker Levels
If abnormal biomarker levels are ignored, cancer has the opportunity to progress unchecked. Untreated NSCLC often metastasizes to the brain, bones, or liver. Bladder cancer, if undetected or untreated, can move from the lining of the bladder into the deeper muscle walls, drastically affecting treatment options and survival rates.
Regular monitoring through the Cyfra 21-1 test allows for early intervention, changing the treatment plan before the disease advances to a stage that is harder to manage.
How to Prepare for the Test
One of the benefits of the Cyfra 21-1 test is that it fits easily into your life with minimal disruption.
- No Fasting Required: You do not need to fast.
- Medication Review: Inform your doctor about any supplements or medications you are taking.
- Activity Level: Avoid strenuous physical activity or intense stress immediately before the test, as extreme physical stress can sometimes temporarily affect biomarker levels.
- The Procedure: A simple blood draw (Serum) is all that is required.
Note: Results typically take 10 Days. This turnaround time allows for the precise immunoassay analysis needed to detect even minute changes in cytokeratin levels.
Empowering Your Health Decisions
Facing the possibility of cancer, or managing a diagnosis, is one of life’s greatest challenges. But you do not have to navigate it blindly.
The Cyfra 21-1 Lab Test provides clarity. It translates the body’s microscopic signals into actionable data, helping you and your healthcare team make informed decisions about treatment, therapy adjustments, and future care.
Take charge of your oncology journey today. Book your Cyfra 21-1 test and get the insights you need.
Frequently Asked Questions – CYFRA 21-1 Tumor Marker Test
What is the CYFRA 21-1 Test?
The CYFRA 21-1 test measures the level of cytokeratin-19 fragments in the blood. These fragments are released into the bloodstream when epithelial cells undergo abnormal changes, such as in certain cancers, and their levels can be used as a tumor marker.
Why is this test done?
This test is primarily used to help detect, monitor, and manage non-small cell lung cancer (NSCLC), especially in the squamous cell subtype, and may also be used in bladder cancer care. Elevated levels can provide insights into disease presence and treatment response.
Who should consider the CYFRA 21-1 test?
Individuals at risk for or undergoing treatment for lung or bladder cancer, those with suspicious imaging results, or patients who require ongoing monitoring of tumor marker levels may benefit from this test. It is usually ordered by a clinician within a broader diagnostic or monitoring plan.
How is the CYFRA 21-1 test performed?
The test is done using a simple blood draw (serum sample) that is analyzed in the laboratory to measure the level of cytokeratin-19 fragments. No special preparation is typically required.
Do I need to fast before the test?
No fasting or special preparation is normally needed for this test. You may eat, drink, and take medications as usual unless your healthcare provider gives specific instructions.
How long does it take to get the results?
Results are typically available within about 10–14 days depending on laboratory processing time.
Can CYFRA 21-1 results diagnose cancer?
No. Elevated CYFRA 21-1 levels alone cannot confirm a cancer diagnosis. The test is a tumor marker used in conjunction with imaging, biopsy, clinical evaluation, and other diagnostic tools. Interpretation should always be done by a healthcare provider.
Can CYFRA 21-1 be elevated in non-cancer conditions?
Yes. Slightly elevated CYFRA 21-1 levels can be seen in some non-cancer conditions such as benign lung disease, liver disease, or kidney dysfunction. Your clinician will interpret results in the full clinical context.
How is CYFRA 21-1 used in monitoring treatment?
Serial measurements of CYFRA 21-1 over time can help clinicians assess how well cancer treatment is working. Falling levels may indicate response to therapy, while rising levels might suggest progression or recurrence.
Do I need a doctor’s referral to book this test?
You can often book this test directly online, but discussing your results and next steps with a healthcare provider is highly recommended.






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