24G Pharmacogenomics & DNA Test – Personalized Medicine & Genetic Insights

Description

24G Pharmacogenomics & DNA Test – Personalized Medicine Based on Your Genetics

The 24G Pharmacogenomics (PGx) & DNA Test from Lab Tests Dubai is a revolutionary genetic testthat analyzes how your DNA affects your body’s response to medications—helping doctors prescribe the right drug, at the right dose, the first time.

Pharmacogenomics (PGx) studies how genetic variations in liver enzymes like CYP2D6, CYP2C19, CYP3A4, and othersinfluence:

• How fast you metabolize drugs
• Whether a medication will work for you
• Your risk of side effects or toxicity

This test is essential for:

• Patients on antidepressants, antipsychotics, or anxiety meds
• Those taking painkillers (opioids, NSAIDs)
• Cardiac patients on blood thinners (e.g., clopidogrel, warfarin)
• People with chronic conditions (diabetes, epilepsy, autoimmune diseases)
• Anyone who’s had bad reactions or no benefit from medications

Using advanced Illumina genotyping technology, this saliva-based test analyzes 24+ key pharmacogenes and provides a clear, actionable report for you and your doctor so you can avoid trial-and-error prescribing and reduce the risk of adverse drug reactions (ADRs).

Available with discreet home saliva collection, Lab Tests Dubai ensures accurate, private, and stress-free testing so you can take control of your treatment with confidence.

Why You Need This Test

If you’ve ever experienced:

• “This antidepressant made me worse, not better.”
• “The painkiller didn’t work, but the next one knocked me out.”
• “I had side effects everyone said were ‘rare’.”

Then your genes may be the reason and this test could prevent future medication mishaps.

You need the 24G Pharmacogenomics Test if:

• You’re starting or struggling with psychiatric meds (SSRIs, SNRIs, antipsychotics)
• You’re on blood thinners, statins, or anti-seizure drugs
• You’ve had unexplained side effects (nausea, fatigue, dizziness, mood swings)
• Your meds don’t work despite correct dosing
• You’re on multiple medications (risk of interactions)
• You’re planning long-term treatment for chronic illness

This test helps:

• Predict drug effectiveness before starting
• Avoid dangerous side effects
• Optimize dosing (poor vs. ultra-rapid metabolizers)
• Reduce trial-and-error (saves time, money, suffering)
• Empower shared decision-making with your doctor

Your genes shouldn’t be a guessing game they should guide your treatment.

Symptoms That Indicate This Test

Consider the PGx Test if you experience:

✅ After Starting Medication:

• Severe side effects (e.g., nausea, insomnia, agitation)
• No improvement in symptoms
• Mood swings, suicidal thoughts, or worsening anxiety
• Extreme fatigue or dizziness
• Unusual reactions others don’t experience

✅ For Chronic Medication Users:

• Frequent dose adjustments
• Multiple meds with unclear results
• History of hospitalization due to ADRs

✅ For High-Risk Individuals:

• Mental health patients (depression, bipolar, PTSD)
• Cardiac patients (on clopidogrel, warfarin, beta-blockers)
• Chronic pain patients (on opioids or gabapentinoids)

These signs may point to genetic drug metabolism issues and this test helps start the right treatment.

Natural Production: How Genes Control Drug Response

Your liver uses enzymes (like CYP450 family) to break down medications.

Genetic variations can make these enzymes:

• Poor Metabolizers (PM) → drugs build up → toxicity risk
• Intermediate Metabolizers (IM) → slower processing
• Normal Metabolizers (NM) → standard response
• Rapid or Ultra-Rapid Metabolizers (RM/UM) → drugs break down too fast → no effect

Key Gene-Drug Pairs:

• CYP2D6: SSRIs (fluoxetine), beta-blockers, opioids (codeine)
• CYP2C19: Clopidogrel (Plavix), antidepressants (citalopram)
• CYP3A4/5: Statins, immunosuppressants
• TPMT: Azathioprine (autoimmune drugs)
• SLCO1B1: Statin-induced muscle pain

The 24G PGx Test identifies these variants so your doctor can choose safer, more effective drugs.

What Happens If Untreated? Risks of Ignoring Pharmacogenetics

Ignoring your genetic drug response can lead to:

⚠️ Adverse Drug Reactions (ADRs) – 6.7% of hospitalizations
⚠️ Treatment Failure – e.g., clopidogrel not working in CYP2C19 poor metabolizers
⚠️ Suicidal Ideation – in CYP2D6 ultra-rapid metabolizers on SSRIs
⚠️ Toxicity – e.g., codeine → morphine overdose in UMs
⚠️ Chronic Suffering – due to ineffective or harmful meds

The good news? PGx testing reduces ADRs by up to 30% and improves outcomes with:

• Personalized drug selection
• Optimized dosing
• Fewer medication switches

Early testing safer, smarter treatment.

How to Prepare for the Test

To ensure accurate results:

✅ No fasting required
✅ Continue your regular medications (do not stop without doctor’s advice)
✅ Avoid eating, drinking (except water), smoking, or chewing gum 30 minutes before
✅ Use the sterile saliva kit provided by Lab Tests Dubai
✅ Follow the step-by-step instructions for collection

A simple saliva sample is collected at home and shipped to the lab no blood, no clinic visit.

Test Overview: Illumina Pharmacogenomics Technology

Report Includes:

• Gene Variants Detected (e.g., CYP2D64, CYP2C192)
• Metabolizer Status (Poor, Normal, Rapid, Ultra-rapid)
• Drug-Specific Recommendations (FDA/CPIC guidelines)
• Actionable Summary for Your Doctor

Note: Results are guidelines always interpret with your physician or pharmacist.

Benefits of the 24G Pharmacogenomics Test

🔹 Avoid Harmful Side Effects
Stop guessing know your risk.

🔹 Improve Treatment Success
Start with the right drug.

🔹 Save Time & Money
Reduce trial-and-error prescribing.

🔹 Empower Your Doctor
Provide science-backed insights.

🔹 Peace of Mind
Know your body’s response in advance.

If you’re tired of medication side effects or no relief, the 24G Pharmacogenomics Test gives you the answers you need in 3–6 weeks.